Lycopene is the natural chemical that gives tomatoes their red hue and is also found in watermelon, pink grapefruit and apricots. Lycopene is an antioxidant that helps repair the damage done to cells by environmental and other stresses .Vitamins are substances that your body needs to function normally. They are natural substances required by the body to grow and develop. Vitamins are contained in food and it is said that a well-balanced diet provides all of the vitamins required. However, there are times, like during pregnancy and childhood, during illness, your body needs more vitamins than usual. It is here multivitamins play a vital role. They are recommended for patients who need extra vitamins, who are not healthy, who cannot eat enough food to obtain the required vitamins etc. Multivitamins represent the preparations which supplement the diet with vitamins, dietary minerals and other nutritional element
Indication and Usage:
Prophylactics supplement in patients affected with lung cancer, prostate cancer, breast cancer, ovarion cancer.
Absorption and Metabolism: Carotenoids are absorbed like fats and transported via the lymphatic system into the liver. Absorption is dependent on the diet. Studies have demonstrated that higher fat diets increase lycopeneabsorption, while cholesterol-lowering drugs reduce its absorption. Also, lycopene from processed tomato products is more readily absorbed than that from raw tomatoes.
After ingestion, lycopene is incorporated into lipid micelles in the small intestine. These micelles are formed from dietary fats and bile acids, and help to solubilize the hydrophobic lycopene and allow it to permeate the intestinal mucosal cells by a passive transport mechanism. Little is known about the liver metabolism of lycopene, but like other carotenoids, lycopene is incorporated into chylomicrons and released into the lymphatic system. In blood plasma, lycopene is eventually distributed into the very low and low density lipoprotein fractions.]Lycopene is mainly distributed to fatty tissues and organs such as the adrenal glands, liver, prostate and testes.
Role in photosynthesis:
Lycopene is a key intermediate in the biosynthesis of many carotenoids .Carotenoids like lycopene are important pigments found in photosynthetic pigment-protein complexes in plants, photosynthetic bacteria, fungi, and algae. They are responsible for the bright colors of fruits and vegetables, perform various functions in photosynthesis, and protect photosynthetic organisms from excessive light damage. Lycopene is a key intermediate in the biosynthesis of many important carotenoids, such as beta-carotene, and xanthophylls.
Antioxidant Properties and Potential Health Benefits:
Lycopene may be the most powerful carotenoid quencher of singlet oxygen, being 100 times more efficient in test tube studies of singlet-oxygen quenching action than vitamin E, which in turn has 125 times the quenching action of glutathione (water soluble)]. Singlet oxygen produced during exposure to ultraviolet light is a primary cause of skin aging. In addition, a lycopene metabolite apo-10'-lycopenal, or ALA, may have an important role in the metabolism of hepatic lipids, and may prevent build up. The build up of lipids in the liver can result in non-alcoholic fatty liver disease, or NAFLD. NAFLD can progress to more serious conditions, such as, fibrosis, cirrhosis, and hepatocellular carcinoma.
Prostate cancer: Early research in men with precancerous changes in their prostate shows that taking 4 mg of lycopene supplements twice daily might delay or prevent progression to prostate cancer. In addition, researchers have surveyed men about their diet and health and found contradictory information about a possible role for lycopene in preventing prostate cancer. Some of these studies show that lycopene from foods, such as tomato products, is associated with a lower risk of developing prostate cancer. But other research shows no association between dietary lycopene intake and prostate cancer risk. However, for men in this study who had a family history of prostate cancer, getting more lycopene from food seemed to offer some protection against getting prostate cancer.
Breast cancer:Several studies have tried to determine whether getting more lycopene from food or taking supplements will help to prevent breast cancer. But findings have not agreed.
Bladder cancer: Research to date suggests that lycopene intake from the diet and lycopene levels in the blood don't affect the risk of getting bladder cancer.
Ovarian cancer:Some research shows that a diet rich in carotenoids, including lycopene, seems to help prevent ovarian cancer in young (premenopausal) women.
Pancreatic cancer: Some research shows that a diet high in lycopene, primarily from tomatoes, seems to lower the risk of getting pancreatic cancer.
Lung cancer:There is some evidence that getting lycopene from foods -- 12 mg/day or more for men, and 6.5 mg/day or more for womenâlowers lung cancer risk in nonsmoking men aged 40 to 75, and nonsmoking women aged 30 to 55.
Cancer of the colon and rectum. Research so far suggests that there is no connection between dietary lycopene and the risk of getting cancer of the colon or rectum.
White pre-cancerous patches in the mouth (oral leukoplakia). Developing clinical research shows that taking 8 mg/day or 4 mg/day of a specific lycopene supplement (LycoRed, Jagsonpal Pharmaceutical) significantly improves oral leukoplakia.
Heart disease. Study results are mixed. Some research shows that women with higher levels of lycopene in their blood have a lower risk of getting heart disease. But other studies show no link between lycopene intake and the risk ofheart attack and stroke in women. In men already at low risk for heart disease, increasing dietary lycopene does not seem to prevent heart attacks.
Eye disease (age related maculopathy):
So far, it appears that dietary lycopene has no effect on getting or preventing age-related maculopathy.
Human papilloma virus (HPV) infection. Women with higher levels of lycopene in their blood seem to get over HPV infections.
"Hardening of the arteries" (atherosclerosis).
Asthma attacks brought on by exercise.
This product should not be used with the following medications because a very serious interaction may occur:
If you are currently using any of the medications listed above, tell your doctor or pharmacist before starting this multivitamin.Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: hydantoins (e.g., phenytoin), methotrexate, pyrimethamine, other vitamin/mineral/nutritionalsupplements.
Lycopene rarely causes side effects, but there are a few reports of diarrhea, nausea, stomach pain, gas, vomiting, indigestion, bloating and appetite loss. If you have an allergy to tomatoes you might want to avoid lycopene supplements in case they trigger an attack.
Lycopene is an antioxidant pigment that gives tomatoes, red peppers, grapefruit, watermelon and other vegetables and fruits their characteristic bright pink or reddish hues. This carotenoid nutrient is common in the Western diet, as these foods are used in many dishes, including pasta sauces. According to MayoClinic.com, lycopene is also naturally present in human serum, skin, the liver, the lungs, the adrenal glands, the colon and the prostate gland. This nutrient is thought to have several beneficial properties and may even have anti-cancer effects, though the research is not yet conclusive.
Warning and Precautions:
Pregnant or lactating women, diabetics, hypoglycemics, and people with know medical condition and/or taking drugs should consult with a license physican and/or pharmacist prior to taking dietary supplements. Keep out of reach of children
Store in cool and dry place.