Proanthocyanidins (also called leukoanthocyanidins) are a class of natural polyphenolicbioflavonoids that are very widespread in nature. Proanthocyanidins appear to be especiallyeffective in neutralizing highly reactive hydroxyl and singlet oxygen radicals. Both of thesereactive oxygen species are involved in inflammatory processes.
Proanthocyanidins also support and enhance the activity of vitamin C, and are known for their ability to help support the health of the body's capillary system and connective tissues. Proanthocyanidins have been shown to bind with collagen fibers, thereby protecting them from premature degradation. This helps maintain the natural elasticity of collagen in skin, joints, arteries, capillaries, and other connective tissues.
This supplement helps support cardiac health by maintaining youthful endothelialfunction, regulating platelet aggregation, and reducing inflammation. It is a powerful protector ofheart and general circulation. It favorably changes a number of metabolic signals towardreduced risk for cardiovascular disease. It is proven to act as a water-soluble antioxidant andhelps lower key inflammatory signals such as CRP, IL6, and TNFa. It is also proven to act at thegene transcription level, helping clear cholesterol, reduce triglycerides, and directly helping thekey inflammatory gene signal known as NF-kappaB.
The main used of Proanthocyanidine are:
Chronic Venous Insufficiency: Proanthocyanidins have been shown to strengthen capillaries in double-blind research.
Capillary Fragility: Proanthocyanidins extracted from grape seeds have been shown to increase capillary strength in people with hypertension and diabetes.
Retinopathy: Found in pine bark, grape seed, and other plant sources, proanthocyanidins may help slow the progression of diabetic retinopathy.
Sunburn: These flavonoids may increase the amount of ultraviolet rays necessary to cause sunburn.
Hypertension: grape seed extract may lower blood pressure in people with mildly elevated bloodpressure.
Pancreatic Insufficiency: grape seed extract saw reduced frequency and intensity of abdominal pain.Other benefits are: